RF Diffusion
Backbone generation with contig or symmetry constraints (RosettaCommons/RFdiffusion).
Paths and inputs
- Upload contig JSON or symmetry files alongside FASTAs under
/inputs. - The service manages
inference.model_directory_path; do not override it. - Write any results under
/outputsfor download.
Example: unconditional monomer
Three designs without symmetry constraints:
inference.output_prefix=default
inference.num_designs=3
contigmap.contigs=[50-200]Example: tetrahedral symmetry
Apply the bundled symmetry config and write outputs under /outputs/def-sym:
--config-name=symmetry
inference.output_prefix=/outputs/def-sym
inference.symmetry=tetrahedral
inference.num_designs=3
contigmap.contigs=[120-120]Submit
Launch from New Job -> RF Diffusion, RF Diffusion 2, or RF Diffusion 3 (Foundry). Keep inputs under /inputs and outputs under /outputs.